28 articles - From Saturday Jan 15 2022 to Friday Jan 21 2022
Guidelines, position statements, white papers, technical reviews, consensus statements, etc…
meta-analyses and systematic reviews
RCT, clinical trials, retrospective studies, etc…
| Ann Rheum Dis |
Accounting for missing data caused by drug cessation in observational comparative effectiveness research: a simulation study. Only multiple imputation and IPW2, which considered both confounding and treatment cessation reasons, produced accurate comparative effectiveness estimates. |
Additional heterologous versus homologous booster vaccination in immunosuppressed patients without SARS-CoV-2 antibody seroconversion after primary mRNA vaccination: a randomised controlled trial. This enhanced humoral and/or cellular immune response supports an additional booster vaccination in non-seroconverted patients irrespective of a heterologous or homologous vaccination regimen. |
Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor. The MHC-peptide-TCR interactions elucidated in our study provide new molecular insights into recognition of a post-translationally modified RA T-cell determinant with a known dominant role in arthritogenic and tolerogenic responses in murine Col2-induced arthritis. |
Tofacitinib and risk of cardiovascular outcomes: results from the Safety of TofAcitinib in Routine care patients with Rheumatoid Arthritis (STAR-RA) study. We did not find evidence for an increased risk of cardiovascular outcomes with tofacitinib in patients with RA treated in the real-world setting; however, tofacitinib was associated with an increased risk of cardiovascular outcomes, although statistically non-significant, in patients with RA with cardiovascular risk factors. |
| Arthritis Care Res (Hoboken) |
Clinical Academic Rheumatology: A Boon for Health Systems. For every $1 generated though office visits by five practicing academic rheumatologists at our institution $12.14 were generated through downstream revenue, which when adjusted for inflation shows stability in the value generated by academic rheumatologists ($10.02 vs $9.37). |
Dosing Variation at Initiation of Adalimumab and Etanercept is not Associated with Clinical Outcomes in Juvenile Idiopathic Arthritis: A Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry study. This study was not able to confirm our hypothesis that increased dosing of TNF inhibitors results in improved treatment outcomes. Although adjustment was performed for risk factors of impaired treatment response, residual confounding by indication likely explains the negative associations found in this study. |
Incidence and prevalence of knee osteoarthritis using codified and narrative data from electronic health records: a population-based study. Our study of a Dutch primary care database showed that current incidence and prevalence estimates based on codified data alone from electronic health records are underestimated. Narrative data can be incorporated in addition to codified data to identify knee OA patients more accurately. |
Patient Perceptions and Preferences Regarding Telemedicine for Rheumatologic Care during the COVID-19 Pandemic. During the pandemic, patients with autoimmune rheumatic diseases frequently had telemedicine visits, the majority via video, and were satisfied with these visits. These results suggest that because patients prefer telemedicine for certain visit reasons, maximizing effective use of telemedicine will require personalized patient scheduling. |
| Arthritis Res Ther |
A role for neutrophils in early enthesitis in spondyloarthritis. Neutrophils with inducible IL-23 production are present in uninflamed human entheseal sites, and neutrophils are prominent in early murine spondyloarthritis-related enthesitis. We propose a role for neutrophils in the early development of enthesitis. |
Characterization and use of the ECV304 autoantigenic citrullinome to understand anti-citrullinated protein/peptide autoantibodies in rheumatoid arthritis. ECV304 cells overexpress two of the PAD isoenzymes capable of citrullinating self-proteins. These autocitrullinated cells constitute a basic and clinical research tool that enable the detection of cit-prot-ACPAs with high diagnostic specificity and allow the identification of the specific cit-proteins targeted by individual RA sera. |
Fibrotic alterations in human annulus fibrosus correlate with progression of intervertebral disc herniation. The characterization of human AF here conducted evidence the presence of fibrosis in degenerated IVD, while highlighting the importance of considering the herniation progression stage, despite the patients' age, for a better understanding of the mechanisms behind AF failure and IVD herniation. |
| Rheumatology (Oxford) |
Utility of the breath-holding test in patients with systemic sclerosis. BHT, a simple and less time-consuming test, shows excellent reliability and significant correlation with Borg scale, SHAQ, and pulmonary parameters. These results suggest that BHT might be a useful surrogate marker of pulmonary capacity in SSc patients. |
Plenty of the editorials are available as full text through the publisher website using the provided link
| Ann Rheum Dis |
Cutaneous signs and mechanisms of inflammasomopathies. The range of possible skin lesions is vast, ranging from urticarial, erysipelas-like and pustular rashes to erythematous patches, violaceous plaques and eventual necrosis and ulceration. This review provides a structured overview of the pathogenesis and the clinical picture with a focus on dermatological aspects of inflammasomopathies. Current treatment options for these conditions are also discussed. |
| Arthritis Care Res (Hoboken) |
Letters to the editors and authors’ replies
| Ann Rheum Dis |
all remaining publications eg case reports, images of the month, etc…
| Ann Rheum Dis |
| Arthritis Rheumatol |
| Rheumatology (Oxford) |